Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
UBE2O
Research Area
Epigenetics, Metabolism
Form
liquid
Recomended Dilution
WB: 1:200-1:2000
Type Clonality
polyclonal
Immunogen
ubiquitin-conjugating enzyme E2O
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
(E3-independent) E2 ubiquitin-conjugating enzyme|E2/E3 hybrid ubiquitin-protein ligase UBE2O|Ubiquitin carrier protein O|Ubiquitin-conjugating enzyme E2 O|Ubiquitin-conjugating enzyme E2 of 230 kDa (Ubiquitin-conjugating enzyme E2-230K)|Ubiquitin-protein
Host
Rabbit
UniProt ID
Q9C0C9
Gene ID
63893
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
141 kDa
Background
E2/E3 hybrid ubiquitin-protein ligase that displays both E2 and E3 ligase activities and mediates monoubiquitination of target proteins(PubMed:23455153, PubMed:24703950). Negatively regulates TRAF6-mediated NF-kappa-B activation independently of its E2 ac