FT-FNab09181
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Size | 100µg |
Storage Conditions | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Applications | ELISA, WB |
Target | UBE2O |
Research Area | Epigenetics, Metabolism |
Form | liquid |
Recomended Dilution | WB: 1:200-1:2000 |
Type Clonality | polyclonal |
Immunogen | ubiquitin-conjugating enzyme E2O |
Minimum Purity | ≥95% as determined by SDS-PAGE |
Synonyms | (E3-independent) E2 ubiquitin-conjugating enzyme|E2/E3 hybrid ubiquitin-protein ligase UBE2O|Ubiquitin carrier protein O|Ubiquitin-conjugating enzyme E2 O|Ubiquitin-conjugating enzyme E2 of 230 kDa (Ubiquitin-conjugating enzyme E2-230K)|Ubiquitin-protein |
Host | Rabbit |
UniProt ID | Q9C0C9 |
Gene ID | 63893 |
Purification | Immunogen affinity purified |
Iso type | IgG |
Reactivity | Human, Mouse |
Observed MW | 141 kDa |
Background | E2/E3 hybrid ubiquitin-protein ligase that displays both E2 and E3 ligase activities and mediates monoubiquitination of target proteins(PubMed:23455153, PubMed:24703950). Negatively regulates TRAF6-mediated NF-kappa-B activation independently of its E2 ac |