Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
HUWE1
Research Area
Epigenetics, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
HECT, UBA and WWE domain containing 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
E3 ubiquitin-protein ligase HUWE1|ARF-binding protein 1 (ARF-BP1)|HECT, UBA and WWE domain-containing protein 1|HECT-type E3 ubiquitin transferase HUWE1|Homologous to E6AP carboxyl terminus homologous protein 9 (HectH9)|Large structure of UREB1 (LASU1)|Mc
Host
Rabbit
UniProt ID
Q7Z6Z7
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
482 kDa
Background
E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Regulates apoptosis by catalyzing the polyubiquitination and degradation of MCL1. Mediates monoubiquitination of DNA polymerase beta(POLB)