Size
              100µg
          
                  
              Storage Conditions
              PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
          
                  
              Applications
              ELISA, WB
          
                  
              Target
              HUWE1
          
                  
              Research Area
              Epigenetics, Metabolism
          
                  
              Form
              liquid
          
                  
              Recomended Dilution
              WB: 1:500-1:2000
          
                  
              Type Clonality
              polyclonal
          
                  
              Immunogen
              HECT, UBA and WWE domain containing 1
          
                  
              Minimum Purity
              ≥95% as determined by SDS-PAGE
          
                  
              Synonyms
              E3 ubiquitin-protein ligase HUWE1|ARF-binding protein 1 (ARF-BP1)|HECT, UBA and WWE domain-containing protein 1|HECT-type E3 ubiquitin transferase HUWE1|Homologous to E6AP carboxyl terminus homologous protein 9 (HectH9)|Large structure of UREB1 (LASU1)|Mc
          
                  
              Host
              Rabbit
          
                  
              UniProt ID
              Q7Z6Z7
          
                  
              Purification
              Immunogen affinity purified
          
                  
              Iso type
              IgG
          
                  
              Reactivity
              Human, Mouse, Rat
          
                  
              Observed MW
              482 kDa
          
                  
              Background
              E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Regulates apoptosis by catalyzing the polyubiquitination and degradation of MCL1. Mediates monoubiquitination of DNA polymerase beta(POLB)