Información del producto
ARHGEF4 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC, WB
Target
ARHGEF4
Research Area
Neuroscience, Signal Transduction
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
Rho guanine nucleotide exchange factor(GEF) 4
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Rho guanine nucleotide exchange factor 4|APC-stimulated guanine nucleotide exchange factor 1 (Asef, Asef1)|ARHGEF4|KIAA1112
Host
Rabbit
UniProt ID
Q9NR80
Gene ID
50649
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
72 kDa
Background
Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required