FT-FNab00562
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Size | 100µg |
Storage Conditions | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Applications | ELISA, IHC, WB |
Target | ARHGEF4 |
Research Area | Neuroscience, Signal Transduction |
Form | liquid |
Recomended Dilution | WB: 1:500-1:2000 |
Type Clonality | polyclonal |
Immunogen | Rho guanine nucleotide exchange factor(GEF) 4 |
Minimum Purity | ≥95% as determined by SDS-PAGE |
Synonyms | Rho guanine nucleotide exchange factor 4|APC-stimulated guanine nucleotide exchange factor 1 (Asef, Asef1)|ARHGEF4|KIAA1112 |
Host | Rabbit |
UniProt ID | Q9NR80 |
Gene ID | 50649 |
Purification | Immunogen affinity purified |
Iso type | IgG |
Reactivity | Human, Mouse |
Observed MW | 72 kDa |
Background | Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required |