FT-FNab00473
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Comprando este producto generará 1 Biopunto. Su cesta contiene un total 1 Biopunto puede ser convertido en un Biobonos Descuento 4.00EUR.
Size | 100µg |
Storage Conditions | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
Applications | ELISA, WB, IHC |
Target | APC |
Research Area | Cancer, Cell Division and Proliferation, Cardiovascular, Signal Transduction |
Form | liquid |
Recomended Dilution | WB: 1:500 - 1:2000 |
Type Clonality | polyclonal |
Immunogen | adenomatous polyposis coli |
Minimum Purity | ≥95% as determined by SDS-PAGE |
Synonyms | Adenomatous polyposis coli protein (Protein APC)|Deleted in polyposis 2.5|APC|DP2.5 |
Host | Rabbit |
UniProt ID | P25054 |
Gene ID | 324 |
Purification | Immunogen affinity purified |
Iso type | IgG |
Reactivity | Human, Mouse |
Observed MW | 300 kDa |
Background | Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte grow |