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APC antibody

FT-FNab00473

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Data sheet

Size 100µg
Storage Conditions PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications ELISA, WB, IHC
Target APC
Research Area Cancer, Cell Division and Proliferation, Cardiovascular, Signal Transduction
Form liquid
Recomended Dilution WB: 1:500 - 1:2000
Type Clonality polyclonal
Immunogen adenomatous polyposis coli
Minimum Purity ≥95% as determined by SDS-PAGE
Synonyms Adenomatous polyposis coli protein (Protein APC)|Deleted in polyposis 2.5|APC|DP2.5
Host Rabbit
UniProt ID P25054
Gene ID 324
Purification Immunogen affinity purified
Iso type IgG
Reactivity Human, Mouse
Observed MW 300 kDa
Background Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte grow

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APC antibody