Información del producto
APC antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
APC
Research Area
Cancer, Cell Division and Proliferation, Cardiovascular, Signal Transduction
Form
liquid
Recomended Dilution
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
adenomatous polyposis coli
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Adenomatous polyposis coli protein (Protein APC)|Deleted in polyposis 2.5|APC|DP2.5
Host
Rabbit
UniProt ID
P25054
Gene ID
324
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
300 kDa
Background
Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte grow