Información del producto
APAF1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP, IF
Target
APAF1
Research Area
Developmental biology
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
apoptotic peptidase activating factor 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Apoptotic protease-activating factor 1 (APAF-1)|APAF1|KIAA0413
Host
Rabbit
UniProt ID
O14727
Gene ID
317
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
140 kDa
Background
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9(Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.