APAF1 antibody View larger

APAF1 antibody

FT-FNab00470

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Data sheet

Size 100µg
Storage Conditions PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications ELISA, WB, IHC, IP, IF
Target APAF1
Research Area Developmental biology
Form liquid
Recomended Dilution WB: 1:500-1:2000
Type Clonality polyclonal
Immunogen apoptotic peptidase activating factor 1
Minimum Purity ≥95% as determined by SDS-PAGE
Synonyms Apoptotic protease-activating factor 1 (APAF-1)|APAF1|KIAA0413
Host Rabbit
UniProt ID O14727
Gene ID 317
Purification Immunogen affinity purified
Iso type IgG
Reactivity Human, Mouse, Rat
Observed MW 140 kDa
Background Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9(Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

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APAF1 antibody