Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC
Target
MGMT
Research Area
Cancer, Immunology, Metabolism
Form
liquid
Recomended Dilution
IHC: 1:50 - 1:500
Type Clonality
polyclonal
Immunogen
O-6-methylguanine-DNA methyltransferase
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Methylated-DNA--protein-cysteine methyltransferase|6-O-methylguanine-DNA methyltransferase (MGMT)|O-6-methylguanine-DNA-alkyltransferase|MGMT
Host
Rabbit
UniProt ID
P16455
Gene ID
4255
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
22 kDa
Background
Involved in the cellular defense against the biological effects of O6-methylguanine(O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suic