Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC
Target
PTCH1
Research Area
Neuroscience, Cell Division and Proliferation
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
Type Clonality
polyclonal
Immunogen
patched homolog 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Protein patched homolog 1 (PTC, PTC1)|PTCH1|PTCH
Host
Rabbit
UniProt ID
Q13635
Gene ID
5727
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Rat
Observed MW
161 kDa
Background
Acts as a receptor for sonic hedgehog(SHH), indian hedgehog(IHH) and desert hedgehog(DHH). Associates with the smoothened protein(SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein