Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC
Target
HMGCR
Research Area
Metabolism
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
Type Clonality
polyclonal
Immunogen
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase)|HMGCR
Host
Rabbit
UniProt ID
P04035
Gene ID
3156
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
120 kDa
Background
HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally