Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
USP49
Research Area
Epigenetics, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:5000
Type Clonality
polyclonal
Immunogen
ubiquitin specific peptidase 49
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Ubiquitin carboxyl-terminal hydrolase 49|Deubiquitinating enzyme 49|Ubiquitin thioesterase 49|Ubiquitin-specific-processing protease 49|USP49
Host
Rabbit
UniProt ID
Q70CQ1
Gene ID
25862
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
73 kDa
Background
Specifically deubiquitinates histone H2B at 'Lys-120'(H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a la