Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
TTK
Research Area
Cell Division and Proliferation, Metabolism
Form
liquid
Recomended Dilution
WB: 1:200-1:2000
Type Clonality
polyclonal
Immunogen
TTK protein kinase
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Dual specificity protein kinase TTK|Phosphotyrosine picked threonine-protein kinase (PYT)|TTK|MPS1|MPS1L1
Host
Rabbit
UniProt ID
P33981
Gene ID
7272
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
97 kDa
Background
Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity(via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.