Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF, IP
Target
TRIM25
Research Area
Epigenetics, Immunology, Metabolism
Form
liquid
Recomended Dilution
WB: 1:200-1:2000
Type Clonality
polyclonal
Immunogen
tripartite motif-containing 25
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
E3 ubiquitin/ISG15 ligase TRIM25|Estrogen-responsive finger protein|RING finger protein 147|RING-type E3 ubiquitin transferase|RING-type E3 ubiquitin transferase TRIM25|Tripartite motif-containing protein 25|Ubiquitin/ISG15-conjugating enzyme TRIM25|Zinc
Host
Rabbit
UniProt ID
Q14258
Gene ID
7706
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
71 kDa
Background
Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for