Información del producto
TREX1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IP
Target
TREX1
Research Area
Metabolism
Form
liquid
Recomended Dilution
WB: 1:200-1:1000
Type Clonality
polyclonal
Immunogen
three prime repair exonuclease 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Three-prime repair exonuclease 1|3'-5' exonuclease TREX1|Deoxyribonuclease III (DNase III)|TREX1
Host
Rabbit
UniProt ID
Q9NSU2
Gene ID
11277
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
32 kDa
Background
Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA(ssDNA) and double-stranded DNA(dsDNA) with mismatched 3' termini. Prevents cell-intrinsic initiation of autoimmunity. Acts by metabolizing DNA fragments from endogenous retroelement