Información del producto
TNFR1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB,IHC, FC
Target
TNFRSF1A
Research Area
Immunology, Cardiovascular, Developmental biology, Signal Transduction
Form
liquid
Recomended Dilution
WB: 1:500-1:5000
Type Clonality
monoclonal
Immunogen
tumor necrosis factor receptor superfamily, member 1A
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Tumor necrosis factor receptor superfamily member 1A|Tumor necrosis factor receptor 1 (TNF-R1)|Tumor necrosis factor receptor type I (TNF-RI, TNFR-I)|p55|p60|Tumor necrosis factor receptor superfamily member 1A, membrane form|Tumor necrosis factor-binding
Host
Mouse
UniProt ID
P19438
Purification
Protein A+G purification
Clone Number
1G4
Iso type
IgG1
Reactivity
Human, Mouse
Observed MW
50 kDa
Background
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation which initiates