Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC, WB, IF, IP
Target
SOCS3
Research Area
Signal Transduction, Developmental biology
Form
liquid
Recomended Dilution
WB: 1:200-1:2000
Type Clonality
polyclonal
Immunogen
suppressor of cytokine signaling 3
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Suppressor of cytokine signaling 3 (SOCS-3)|Cytokine-inducible SH2 protein 3 (CIS-3)|STAT-induced STAT inhibitor 3 (SSI-3)|SOCS3|CIS3|SSI3
Host
Rabbit
UniProt ID
O14543
Gene ID
9021
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
30 kDa
Background
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by bi