Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF
Target
SHKBP1
Research Area
Neuroscience
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
SH3KBP1 binding protein 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
SH3KBP1-binding protein 1|SETA-binding protein 1|SHKBP1|SB1
Host
Rabbit
UniProt ID
Q8TBC3
Gene ID
92799
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
76 kDa
Background
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.