Información del producto
SCUBE3 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
SCUBE3
Research Area
Neuroscience, Cardiovascular, Developmental biology, Signal Transduction
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
signal peptide, CUB domain, EGF-like 3
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Signal peptide, CUB and EGF-like domain-containing protein 3|SCUBE3|CEGF3
Host
Rabbit
UniProt ID
Q8IX30
Gene ID
222663
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
130 kDa
Background
Binds to TGFBR2 and activates TGFB signaling. In lung cancer cells, could serve as an endogenous autocrine and paracrine ligand of TGFBR2, which could regulate TGFBR2 signaling and hence modulate epithelial-mesenchymal transition and cancer progression.