Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
SCAP
Research Area
Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
SREBF chaperone
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Sterol regulatory element-binding protein cleavage-activating protein (SCAP, SREBP cleavage-activating protein)|SCAP|KIAA0199
Host
Rabbit
UniProt ID
Q12770
Gene ID
22937
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
140 kDa,96 kDa
Background
Escort protein required for cholesterol as well as lipid homeostasis. Regulates export of the SCAP/SREBF complex from the ER upon low cholesterol. Formation of a ternary complex with INSIG at high sterol concentrations leads to masking of an ER-export sig