Información del producto
RNF135 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
RNF135
Research Area
Epigenetics, Immunology, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
ring finger protein 135
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
E3 ubiquitin-protein ligase RNF135|RIG-I E3 ubiquitin ligase (REUL)|RING finger protein 135|RING finger protein leading to RIG-I activation (Riplet)|RING-type E3 ubiquitin transferase RNF135|RNF135
Host
Rabbit
UniProt ID
Q8IUD6
Gene ID
84282
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
48 kDa
Background
Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production.