Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
REC8
Research Area
Cell Division and Proliferation, Metabolism, Developmental biology
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
REC8 homolog(yeast)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Meiotic recombination protein REC8 homolog|Cohesin Rec8p|REC8|REC8L1
Host
Rabbit
UniProt ID
O95072
Gene ID
9985
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
85-95 kDa
Background
Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromer