Información del producto
RB1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP
Target
RB1
Research Area
Metabolism, Immunology, Cancer, Developmental biology, Cell Division and Proliferation
Form
liquid
Recomended Dilution
WB: 1:1000-1:3000
Type Clonality
polyclonal
Immunogen
retinoblastoma 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Retinoblastoma-associated protein|p105-Rb|p110-RB1|pRb (Rb)|pp110|RB1
Host
Rabbit
UniProt ID
P06400
Gene ID
5925
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
110 kDa
Background
Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E