Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP
Target
CRADD
Research Area
Signal Transduction, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
CASP2 and RIPK1 domain containing adaptor with death domain
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Death domain-containing protein CRADD|Caspase and RIP adapter with death domain|RIP-associated protein with a death domain|CRADD|RAIDD
Host
Rabbit
UniProt ID
P78560
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
23 kDa
Background
RAIDD, also named as CRADD, is an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. CRADD interacts with BCL10 thro