Información del producto
PPM1A antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
PPM1A
Research Area
Signal Transduction, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
protein phosphatase 1A(formerly 2C), magnesium-dependent, alpha isoform
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Protein phosphatase 1A|Protein phosphatase 2C isoform alpha (PP2C-alpha)|Protein phosphatase IA|PPM1A|PPPM1A
Host
Rabbit
UniProt ID
P35813
Gene ID
5494
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
42 kDa
Background
Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylate