Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
PMS2
Research Area
Epigenetics, Metabolism, Cancer, Immunology, Developmental biology
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
monoclonal
Immunogen
PMS2 postmeiotic segregation increased 2
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Mismatch repair endonuclease PMS2|DNA mismatch repair protein PMS2|PMS1 protein homolog 2|PMS2|PMSL2
Host
Mouse
UniProt ID
P54278
Gene ID
5395
Purification
Protein A+G purification
Clone Number
4B8
Iso type
IgG1
Reactivity
Human, Mouse, Rat
Observed MW
100KD
Background
Component of the post-replicative DNA mismatch repair system(MMR). Heterodimerizes with MLH1 to form MutL alpha. DNA repair is initiated by MutS alpha(MSH2-MSH6) or MutS beta(MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the hete