Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
PFN2
Research Area
Neuroscience
Form
liquid
Recomended Dilution
WB: 1:1000-1:5000
Type Clonality
monoclonal
Immunogen
profilin 2
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Profilin-2|Profilin II|PFN2
Host
Mouse
UniProt ID
P35080
Gene ID
5217
Purification
Protein A+G purification
Clone Number
5D4
Iso type
IgG1
Reactivity
Human, Mouse, Rat
Observed MW
15 kDa
Background
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.