Información del producto
NOTCH3 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP
Target
NOTCH3
Research Area
Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
Notch homolog 3
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Neurogenic locus notch homolog protein 3 (Notch 3)|Notch 3 extracellular truncation|Notch 3 intracellular domain|NOTCH3
Host
Rabbit
UniProt ID
Q9UM47
Gene ID
4854
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
250-260 kDa, 100 kDa
Background
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH