Información del producto
NOTCH1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP
Target
NOTCH1
Research Area
Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience, Stem Cells
Form
liquid
Recomended Dilution
WB: 1:500-1:1000
Type Clonality
polyclonal
Immunogen
Notch homolog 1, translocation-associated(Drosophila)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Neurogenic locus notch homolog protein 1 (Notch 1, hN1)|Translocation-associated notch protein TAN-1|Notch 1 extracellular truncation (NEXT)|Notch 1 intracellular domain (NICD)|NOTCH1|TAN1
Host
Rabbit
UniProt ID
P46531
Gene ID
4851
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
270 kDa,120kd
Background
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH