Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF, IHC
Target
NET1
Research Area
Signal Transduction, Metabolism, Cancer, Immunology
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
neuroepithelial cell transforming 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Neuroepithelial cell-transforming gene 1 protein|Proto-oncogene p65 Net1|Rho guanine nucleotide exchange factor 8|NET1|ARHGEF8
Host
Rabbit
UniProt ID
Q7Z628
Gene ID
10276
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
62-68 kDa
Background
Acts as guanine nucleotide exchange factor(GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.