Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
MSH2
Research Area
Epigenetics, Metabolism, Cancer, Immunology, Developmental biology
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
monoclonal
Immunogen
mutS homolog 2, colon cancer, nonpolyposis type 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
DNA mismatch repair protein Msh2 (hMSH2)|MutS protein homolog 2|MSH2
Host
Mouse
UniProt ID
P43246
Gene ID
4436
Purification
Protein A+G purification
Clone Number
7C1
Iso type
IgG2a
Reactivity
Human
Observed MW
105 kDa
Background
Component of the post-replicative DNA mismatch repair system(MMR). Forms two different heterodimers: MutS alpha(MSH2-MSH6 heterodimer) and MutS beta(MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodime