Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
MMP12
Research Area
Cardiovascular, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:1000
Type Clonality
polyclonal
Immunogen
matrix metallopeptidase 12(macrophage elastase)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Macrophage metalloelastase (MME)|Macrophage elastase (ME, hME)|Matrix metalloproteinase-12 (MMP-12)|MMP12|HME
Host
Rabbit
UniProt ID
P39900
Gene ID
4321
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
54 kDa, 45 kDa
Background
MMP12(Matrix metalloproteinase-12) is a 54 kDa proenzyme that is processed into a 45 kDa and then a 22 kDa active form(15723202). MMP9 and MMP12 promote intimal thickening by independent cleavage of N-cadherin, which elevates vascular smooth muscle cell p