Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
MIB2
Research Area
Signal Transduction
Form
liquid
Recomended Dilution
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
mindbomb homolog 2(Drosophila)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
E3 ubiquitin-protein ligase MIB2|Mind bomb homolog 2|Novel zinc finger protein (Novelzin)|Putative NF-kappa-B-activating protein 002N|RING-type E3 ubiquitin transferase MIB2|Skeletrophin|Zinc finger ZZ type with ankyrin repeat domain protein 1|MIB2|SKD|ZZ
Host
Rabbit
UniProt ID
Q96AX9
Gene ID
142678
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
74 kDa, 82 kDa, 110 kDa
Background
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Del