Información del producto
MEX3C antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
MEX3C
Research Area
Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
mex-3 homolog C(C. elegans)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
RNA-binding E3 ubiquitin-protein ligase MEX3C|RING finger and KH domain-containing protein 2|RING finger protein 194|RING-type E3 ubiquitin transferase MEX3C|MEX3C|RKHD2|RNF194
Host
Rabbit
UniProt ID
Q5U5Q3
Gene ID
51320
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
69 kDa
Background
E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase