Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC, WB, IF
Target
MDM2
Research Area
Epigenetics, Metabolism, Immunology, Cancer, Cell Division and Proliferation
Form
liquid
Recomended Dilution
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
Mdm2 p53 binding protein homolog ( Mouse )
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
E3 ubiquitin-protein ligase Mdm2|Double minute 2 protein (Hdm2)|Oncoprotein Mdm2|RING-type E3 ubiquitin transferase Mdm2|p53-binding protein Mdm2|MDM2
Host
Rabbit
UniProt ID
Q00987
Gene ID
4193
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
50 kDa
Background
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpres