Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF, IHC
Target
MCL1
Research Area
Stem Cells, Cancer, Metabolism, Developmental biology
Form
liquid
Recomended Dilution
WB: 1:1000-1:10000
Type Clonality
monoclonal
Immunogen
myeloid cell leukemia sequence 1(BCL2-related)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Induced myeloid leukemia cell differentiation protein Mcl-1|Bcl-2-like protein 3 (Bcl2-L-3)|Bcl-2-related protein EAT/mcl1|mcl1/EAT|MCL1|BCL2L3
Host
Mouse
UniProt ID
Q07820
Gene ID
4170
Purification
Protein A+G purification
Clone Number
6F10
Iso type
IgG2a
Reactivity
Human
Observed MW
37 kDa
Background
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promot