Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
MBD2
Research Area
Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
methyl-CpG binding domain protein 2
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Methyl-CpG-binding domain protein 2|Demethylase (DMTase)|Methyl-CpG-binding protein MBD2|MBD2
Host
Rabbit
UniProt ID
Q9UBB5
Gene ID
8932
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Rat
Observed MW
43-45 kDa
Background
Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role i