Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IP
Target
MARCHF8
Research Area
Signal Transduction, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:1000
Type Clonality
polyclonal
Immunogen
membrane-associated ring finger(C3HC4) 8
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
E3 ubiquitin-protein ligase MARCHF8|Cellular modulator of immune recognition (c-MIR)|Membrane-associated RING finger protein 8|Membrane-associated RING-CH protein VIII (MARCH-VIII)|RING finger protein 178|RING-type E3 ubiquitin transferase MARCHF8|MARCHF8
Host
Rabbit
UniProt ID
Q5T0T0
Gene ID
220972
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
33kd
Background
E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and en