Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
LATS1
Research Area
Signal Transduction, Metabolism
Form
liquid
Recomended Dilution
WB: 1:200-1:1000
Type Clonality
polyclonal
Immunogen
LATS, large tumor suppressor, homolog 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Serine/threonine-protein kinase LATS1|Large tumor suppressor homolog 1|WARTS protein kinase (h-warts)|LATS1|WARTS
Host
Rabbit
UniProt ID
O95835
Gene ID
9113
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
140 kDa
Background
Negative regulator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST