Información del producto
KEAP1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC, WB, IF
Target
KEAP1
Research Area
Cancer, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:1000
Type Clonality
monoclonal
Immunogen
kelch-like ECH-associated protein 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Kelch-like ECH-associated protein 1|Cytosolic inhibitor of Nrf2 (INrf2)|Kelch-like protein 19|KEAP1|INRF2|KIAA0132|KLHL19
Host
Mouse
UniProt ID
Q14145
Gene ID
9817
Purification
Protein A+G purification
Clone Number
9E2
Iso type
IgG2a
Reactivity
Human, Mouse, Rat
Observed MW
55-70 kDa
Background
Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repress