Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
INVS
Research Area
Signal Transduction, Metabolism, Developmental biology
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
inversin
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Inversin|Inversion of embryo turning homolog|Nephrocystin-2|INVS|INV|NPHP2
Host
Rabbit
UniProt ID
Q9Y283
Gene ID
27130
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
110-115 kDa
Background
Required for normal renal development and establishment of left-right axis. Probably acts as a molecular switch between different Wnt signaling pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled(DVL1) for degradation by the u