Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
GZMM
Research Area
Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
granzyme M(lymphocyte met-ase 1)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Granzyme M|Met-1 serine protease (Hu-Met-1)|Met-ase|Natural killer cell granular protease|GZMM|MET1
Host
Rabbit
UniProt ID
P51124
Gene ID
3004
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
30 kDa
Background
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.