Información del producto
GZMB antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
GZMB
Research Area
Cancer, Immunology, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
granzyme B
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Granzyme B|C11|CTLA-1|Cathepsin G-like 1 (CTSGL1)|Cytotoxic T-lymphocyte proteinase 2 (Lymphocyte protease)|Fragmentin-2|Granzyme-2|Human lymphocyte protein (HLP)|SECT|T-cell serine protease 1-3E|GZMB|CGL1|CSPB|CTLA1|GRB
Host
Rabbit
UniProt ID
P10144
Gene ID
3002
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
33 kDa
Background
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases(aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3,-