Información del producto
FANCM antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
FANCM
Research Area
Epigenetics, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
Fanconi anemia, complementation group M
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Fanconi anemia group M protein (Protein FACM)|ATP-dependent RNA helicase FANCM|Fanconi anemia-associated polypeptide of 250 kDa (FAAP250)|Protein Hef ortholog|FANCM|KIAA1596
Host
Rabbit
UniProt ID
Q8IYD8
Gene ID
57697
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
250 kDa, 232 kDa
Background
ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. Binds to ssDNA but not to dsDNA. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions.