Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC, WB, IP
Target
FADD
Research Area
Immunology, Signal Transduction
Form
liquid
Recomended Dilution
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
Fas(TNFRSF6)-associated via death domain
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
FAS-associated death domain protein|FAS-associating death domain-containing protein|Growth-inhibiting gene 3 protein|Mediator of receptor induced toxicity|FADD|MORT1
Host
Rabbit
UniProt ID
Q13158
Gene ID
8772
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
26 kDa
Background
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas(CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex(DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiate