Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF, IHC
Target
DKK1
Research Area
Signal Transduction, Developmental biology
Form
liquid
Recomended Dilution
WB: 1:500-1:1000
Type Clonality
polyclonal
Immunogen
dickkopf homolog 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Dickkopf-related protein 1 (Dickkopf-1, Dkk-1, hDkk-1)|SK|DKK1
Host
Rabbit
UniProt ID
O94907
Gene ID
22943
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
30-35 kDa
Background
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they