Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
CHRNA7
Research Area
Neuroscience, Signal Transduction
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
monoclonal
Immunogen
cholinergic receptor, nicotinic, alpha 7
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Neuronal acetylcholine receptor subunit alpha-7|CHRNA7|NACHRA7
Host
Mouse
UniProt ID
P36544
Gene ID
89832
Purification
Protein A+G purification
Clone Number
4B8
Iso type
IgG2a
Reactivity
Human
Observed MW
56 kDa
Background
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.