Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC, WB,IF,IP
Target
CASP8
Research Area
Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:5000
Type Clonality
monoclonal
Immunogen
caspase 8, apoptosis-related cysteine peptidase
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Caspase-8 (CASP-8)|Apoptotic cysteine protease|Apoptotic protease Mch-5|CAP4|FADD-homologous ICE/ced-3-like protease|FADD-like ICE (FLICE)|ICE-like apoptotic protease 5|MORT1-associated ced-3 homolog (MACH)|Caspase-8 subunit p18|Caspase-8 subunit p10|CASP
Host
Mouse
UniProt ID
Q14790
Purification
Protein A+G purification
Clone Number
2C2
Iso type
IgG1
Reactivity
Human
Observed MW
50-55 kDa, 25-32 kDa
Background
Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential interme